Tear production, intraocular pressure and conjunctival microbiota, cytology and histology of New Zealand rabbits (Oryctolagus cuniculus)

The purpose of this study was to establish reference values for selected ophthalmic diagnostic tests in New Zealand rabbits (Oryctolagus cuniculus). A total of 22 adult male rabbits were used. The ophthalmic tests included evaluation of tear production with Schirmer tear test 1(STT1) and Endodontic...

Descripción completa

Detalles Bibliográficos
Autores: Oriá, Arianne P., Gomes Junior, Deusdete C., Arraes, Elane A., Estrela-lima, Alessandra, Pinna, Melissa H., Meneses, Íris D.s., Martins Filho, Emanoel F. [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/114156
Acceso en línea:http://dx.doi.org/10.1590/S0100-736X2014001000016
http://hdl.handle.net/11449/114156
Access Level:acceso abierto
Palabra clave:Produção lacrimal
pressão intraocular
coelhos Nova Zelândia
Oryctolagus cuniculus
lagomorfos
oftalmologia
teste lacrimal de Schirmer
tonometria
tira endodôntica de papel absorvente
Tear production
intraocular pressure
conjunctival microbiota
New Zealand rabbits
lagomorphs
ophthalmology
Schirmer tear test
tonometry
endodontic paper point
Descripción
Sumario:The purpose of this study was to establish reference values for selected ophthalmic diagnostic tests in New Zealand rabbits (Oryctolagus cuniculus). A total of 22 adult male rabbits were used. The ophthalmic tests included evaluation of tear production with Schirmer tear test 1(STT1) and Endodontic absorbent paper point tear test (EAPPTT) using two different commercial brand materials. Applanation tonometry, Culture of the conjunctival bacterial flora, , conjunctival cytology and conjunctival histology were also performed. Mean (±SD) for STT1, EAPPTTa, EAPPTTb and IOP was 7.27±2.51mm/min, 12.43±1.69mm/min, 15.24±2.07mm/min, 12.89±2.80mm Hg, respectively. Staphylococcus epidermidis, Staphylococcus sp. and Bacillus sp. were predominant. The cytological evaluation revealed the presence columnar epithelial cells, superficial squamous keratinized cells, lymphocytes, heterophils, red blood cells, mucus and bacteria. The histological analysis revealed a stratified epithelium, characterized by the presence of columnar epithelial cells with a large number of goblet cells. The reported data can be used for therapeutic or experimental purposes.