Whole-genome sequencing of parvoviruses from wild and domestic animals in Brazil provides new insights into parvovirus distribution and diversity

Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified. In this study, we used high-throughput sequencing (HTS) to investigate the diversity of parvoviruses infecting wild and domestic...

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Detalhes bibliográficos
Autores: Souza, William Marciel de, Dennis, Tristan Philip Wesley, Fumagalli, Marcílio Jorge, Araujo, Jansen de, Santos Jr, Gilberto Sabino, Maia, Felipe Gonçalves Motta, Acrani, Gustavo Olszanski, Carrasco, Adriano de Oliveira Torres, Romeiro, Marilia Farignoli, Modha, Sejal, Vieira, Luiz Carlos, Ometto, Tatiana Lopes, Queiroz, Luzia Helena, Durigon, Edison Luiz, Nunes, Márcio Roberto Teixeira, Figueiredo, Luiz Tadeu Moraes, Gifford, Robert James
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Recursos:Instituto Evandro Chagas (IEC)
Repositorio:Repositório Digital do Instituto Evandro Chagas (Patuá)
Idioma:inglés
OAI Identifier:oai:patua.iec.gov.br:iec/3866
Acesso em linha:https://patua.iec.gov.br/handle/iec/3866
Access Level:acceso abierto
Palavra-chave:Parvovirus / patogenicidade
Infecções por Parvoviridae / veterinária
Animais Selvagens / virologia
Animais Domésticos / virologia
Genoma Viral / genética
Descrição
Resumo:Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified. In this study, we used high-throughput sequencing (HTS) to investigate the diversity of parvoviruses infecting wild and domestic animals in Brazil. We identified 21 parvovirus sequences (including twelve nearly complete genomes and nine partial genomes) in samples derived from rodents, bats, opossums, birds and cattle in Pernambuco, São Paulo, Paraná and Rio Grande do Sul states. These sequences were investigated using phylogenetic and distance-based approaches, and were thereby classified into eight parvovirus species (six of which have not been described previously), representing six distinct genera in the subfamily Parvovirinae. Our findings extend the known biogeographic range of previously characterized parvovirus species, and the known host range of three parvovirus genera (Dependovirus, Aveparvovirus, and Tetraparvovirus). Moreover, our investigation provides a window into the ecological dynamics of parvovirus infections in vertebrates, revealing that many parvovirus genera contain well-defined sub-lineages that circulate widely throughout the world within particular taxonomic groups of hosts.

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