Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia

Considering the importance and severity of feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infections, information on laboratory abnormalities can determine the prognosis of infected cats. This study aimed to determine the laboratory alterations of domiciled asymptomatics cats n...

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Authors: Carvalho Lacerda, Luciana, Nascimento da Silva, Aísla, Dálety Santos Cruz, Rebeca, de Souza Freitas, Jéssica, Abou Said, Roueda, Dias Munhoz, Alexandre
Format: article
Status:Published version
Publication Date:2021
Country:Brasil
Institution:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
Repository:Brazilian Journal of Veterinary Medicine
Language:English
OAI Identifier:oai:ojs.rbmv.org:article/1100
Online Access:https://bjvm.org.br/BJVM/article/view/1100
Access Level:Open access
Keyword:Bilirrubina, retrovírus, FIV, FeLV
Bilirubin, retroviruses, FIV, FeLV
id BR_0d161d7b34ca50c3ccf1ecf94c31cb8e
oai_identifier_str oai:ojs.rbmv.org:article/1100
network_acronym_str BR
network_name_str Brasil
repository_id_str
dc.title.none.fl_str_mv Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
Aspectos hematológicos e bioquímicos de gatos naturalmente infectados pelos vírus da imunodeficiência felina e da leucemia felina
title Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
spellingShingle Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
Carvalho Lacerda, Luciana
Bilirrubina, retrovírus, FIV, FeLV
Bilirubin, retroviruses, FIV, FeLV
title_short Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
title_full Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
title_fullStr Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
title_full_unstemmed Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
title_sort Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemia
dc.creator.none.fl_str_mv Carvalho Lacerda, Luciana
Nascimento da Silva, Aísla
Dálety Santos Cruz, Rebeca
de Souza Freitas, Jéssica
Abou Said, Roueda
Dias Munhoz, Alexandre
author Carvalho Lacerda, Luciana
author_facet Carvalho Lacerda, Luciana
Nascimento da Silva, Aísla
Dálety Santos Cruz, Rebeca
de Souza Freitas, Jéssica
Abou Said, Roueda
Dias Munhoz, Alexandre
author_role author
author2 Nascimento da Silva, Aísla
Dálety Santos Cruz, Rebeca
de Souza Freitas, Jéssica
Abou Said, Roueda
Dias Munhoz, Alexandre
author2_role author
author
author
author
author
dc.subject.por.fl_str_mv Bilirrubina, retrovírus, FIV, FeLV
Bilirubin, retroviruses, FIV, FeLV
topic Bilirrubina, retrovírus, FIV, FeLV
Bilirubin, retroviruses, FIV, FeLV
description Considering the importance and severity of feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infections, information on laboratory abnormalities can determine the prognosis of infected cats. This study aimed to determine the laboratory alterations of domiciled asymptomatics cats naturally infected by FIV and/or FeLV in Northeastern Brazil. Blood samples from 200 cats were evaluated by nested-PCR and commercial immunochromatographic test for diagnosis of these infections. Complete blood count (CBC) and serum biochemistry analyses were performed to evaluate laboratory abnormalities. CBC and biochemical values of cats tested positive for FIV and/or FeLV were tabulated for the presence or absence of changes and analyzed using the chi-square test with Yates correction or Fisher’s exact test for each variable, with a confidence interval of 95%. The total frequency was 6% (12/200) and 3% (6/200) for FIV and FeLV, respectively. The presence of hyperbilirubinemia (total, direct, and indirect) was the only change observed in cats positive for FIV compared to FIV-negative controls (p<0.05). We believe that laboratory changes compatible with immunosuppressive conditions should be more frequent in FIV/FeLV positive cats that already present clinical signs of the disease.
publishDate 2021
dc.date.none.fl_str_mv 2021-05-13
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
peer reviewed
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://bjvm.org.br/BJVM/article/view/1100
10.29374/2527-2179.bjvm110020
url https://bjvm.org.br/BJVM/article/view/1100
identifier_str_mv 10.29374/2527-2179.bjvm110020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://bjvm.org.br/BJVM/article/view/1100/1008
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Medicine; Vol. 42 No. 1 (2020); e110020
Revista Brasileira de Medicina Veterinária; v. 42 n. 1 (2020); e110020
2527-2179
0100-2430
reponame:Brazilian Journal of Veterinary Medicine
instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron:SBMV
instname_str Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron_str SBMV
institution SBMV
reponame_str Brazilian Journal of Veterinary Medicine
collection Brazilian Journal of Veterinary Medicine
repository.name.fl_str_mv Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
repository.mail.fl_str_mv contato.rbmv@gmail.com
_version_ 1853661254308069376
spelling Hematological and biochemical aspects of cats naturally infected with feline immunodeficiency virus and feline leukemiaAspectos hematológicos e bioquímicos de gatos naturalmente infectados pelos vírus da imunodeficiência felina e da leucemia felinaBilirrubina, retrovírus, FIV, FeLVBilirubin, retroviruses, FIV, FeLVConsidering the importance and severity of feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infections, information on laboratory abnormalities can determine the prognosis of infected cats. This study aimed to determine the laboratory alterations of domiciled asymptomatics cats naturally infected by FIV and/or FeLV in Northeastern Brazil. Blood samples from 200 cats were evaluated by nested-PCR and commercial immunochromatographic test for diagnosis of these infections. Complete blood count (CBC) and serum biochemistry analyses were performed to evaluate laboratory abnormalities. CBC and biochemical values of cats tested positive for FIV and/or FeLV were tabulated for the presence or absence of changes and analyzed using the chi-square test with Yates correction or Fisher’s exact test for each variable, with a confidence interval of 95%. The total frequency was 6% (12/200) and 3% (6/200) for FIV and FeLV, respectively. The presence of hyperbilirubinemia (total, direct, and indirect) was the only change observed in cats positive for FIV compared to FIV-negative controls (p<0.05). We believe that laboratory changes compatible with immunosuppressive conditions should be more frequent in FIV/FeLV positive cats that already present clinical signs of the disease.Considerando a importância e a gravidade das infecções pelo vírus da imunodeficiência felina (FIV) e pelo vírus da leucemia felina (FeLV), informações sobre as alterações laboratoriais são determinantes no prognóstico dos pacientes. Objetivou-se com este estudo determinar as alterações laboratoriais de gatos assintomáticos domiciliados, naturalmente infectados pelo FIV e/ou FeLV na “oculto para revisão” Brasil. Amostras de sangue de 200 gatos foram avaliadas pela técnica de nested-PCR e pelo teste comercial imunocromatográfico para o diagnóstico dessas infecções. Contagem de células sanguíneas (CCS) e bioquímica sérica foram realizadas para avaliar as alterações laboratoriais. A CCS e bioquímicos dos animais positivos para FIV e/ou FeLV foram tabulados quanto a presença ou ausência de alterações e analisados através do teste qui-quadrado com correção de Yates ou teste exato de Fisher para cada variável, com intervalo de confiança de 95%. A frequência total foi de 6% (12/200) e 3% (6/200) para FIV e FeLV, respectivamente. A presença de hiperbilirrubinemia (total, direta e indireta) foi a única alteração observada nos gatos positivos para FIV em relação aos animais negativos (p < 0,05). Acreditamos que alterações laboratoriais compatíveis com quadros de imunossupressão devam ser mais frequentes em gatos FIV/FeLV positivos que já apresentem sinais clínicos da doença. Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2021-05-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfhttps://bjvm.org.br/BJVM/article/view/110010.29374/2527-2179.bjvm110020Brazilian Journal of Veterinary Medicine; Vol. 42 No. 1 (2020); e110020Revista Brasileira de Medicina Veterinária; v. 42 n. 1 (2020); e1100202527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVenghttps://bjvm.org.br/BJVM/article/view/1100/1008Copyright (c) 2020 Luciana Carvalho Lacerda, Aísla Nascimento da Silva, Rebeca Dálety Santos Cruz, Jéssica de Souza Freitas, Alexandre Munhoz, Roueda Abou Saidhttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess Carvalho Lacerda, Luciana Nascimento da Silva, Aísla Dálety Santos Cruz, Rebeca de Souza Freitas, Jéssica Abou Said, Roueda Dias Munhoz, Alexandre2024-07-16T07:51:47Zoai:ojs.rbmv.org:article/1100Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2024-07-16T07:51:47Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false
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