Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi

Acesso Aberto

Detalhes bibliográficos
Autores: Almeida, Maria Angela Ornelas de, Jesus, E. E. V., Atta, Maria Luiza Brito de Sousa, Alves, L. C., Berne, M. E. A., Atta, Ajax Mercês
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2005
País:Brasil
Recursos:Universidade Federal da Bahia (UFBA)
Repositorio:Repositório Institucional da UFBA
Idioma:inglés
OAI Identifier:oai:repositorio.ufba.br:ri/6603
Acesso em linha:http://www.repositorio.ufba.br/ri/handle/ri/6603
Access Level:acceso abierto
Palavra-chave:Leishmania chagasi
Natural canine visceral leishmaniasis
Clinical signs and laboratory markers
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dc.title.pt_BR.fl_str_mv Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
dc.title.alternative.pt_BR.fl_str_mv Veterinary Parasitology
title Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
spellingShingle Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
Almeida, Maria Angela Ornelas de
Leishmania chagasi
Natural canine visceral leishmaniasis
Clinical signs and laboratory markers
title_short Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_full Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_fullStr Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_full_unstemmed Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_sort Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
dc.creator.none.fl_str_mv Almeida, Maria Angela Ornelas de
Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
Almeida, Maria Angela Ornelas de
Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
author Almeida, Maria Angela Ornelas de
author_facet Almeida, Maria Angela Ornelas de
Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
author_role author
author2 Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
author2_role author
author
author
author
author
dc.subject.por.fl_str_mv Leishmania chagasi
Natural canine visceral leishmaniasis
Clinical signs and laboratory markers
topic Leishmania chagasi
Natural canine visceral leishmaniasis
Clinical signs and laboratory markers
description Acesso Aberto
publishDate 2005
dc.date.issued.fl_str_mv 2005-02-28
dc.date.accessioned.fl_str_mv 2012-08-17T19:41:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6603
dc.identifier.issn.none.fl_str_mv 0304-4017
dc.identifier.number.pt_BR.fl_str_mv v. 127, n. 3–4
identifier_str_mv 0304-4017
v. 127, n. 3–4
url http://www.repositorio.ufba.br/ri/handle/ri/6603
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.vetpar.2004.10.010
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/6603/1/%28168%29.pdf
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spelling 2012-08-17T19:41:02Z2005-02-280304-4017http://www.repositorio.ufba.br/ri/handle/ri/6603v. 127, n. 3–4Acesso AbertoHuman visceral leishmaniasis is endemic in the northeast of Brazil, where the domestic dog is an important parasite reservoir in the infectious cycle of Leishmania chagasi. In this study, we evaluated the clinical signs of canine visceral leishmaniasis (CVL), serum protein profile and the antileishmanial IgG antibody production in 86 dogs living in northeast endemic areas of leishmaniasis. Thirty dogs from a leishmaniasis-free area were used as a control group. The major clinical signs of CVL seen were emaciation and skin ulcers (80%), followed by onychogryphosis and conjunctivitis (73%). Depilation was observed in 60% of animals while lymphadenomegaly, splenomegaly, liver enlargement or kidney involvement was less frequent (≤20%). VL seropositive dogs presented with serum hyperproteinemia, hypoalbuminemia, hypergammaglobulinemia and decreased albumin/globulin ratio. A lower sensitivity and higher specificity was observed for promastigote indirect fluorescent antibody test (IFAT) (83 and 100%, respectively) compared with enzyme-linked immunosorbent assay (ELISA) (94 and 90%), which uses a crude extract of Leishmania. There was a positive correlation between IFAT and ELISA titers of antileishmanial IgG antibodies (Spearman test, P < 0.05), which was augmented in CVL dogs. This study found that the determination of serum protein, A/G ratio and the use of two different leishmanial serological tests like IFAT and ELISA are essential in CVL screening.Elsevierhttp://dx.doi.org/10.1016/j.vetpar.2004.10.010reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeishmania chagasiNatural canine visceral leishmaniasisClinical signs and laboratory markersClinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasiVeterinary Parasitologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessAlmeida, Maria Angela Ornelas deJesus, E. E. V.Atta, Maria Luiza Brito de SousaAlves, L. C.Berne, M. E. A.Atta, Ajax MercêsAlmeida, Maria Angela Ornelas deJesus, E. E. V.Atta, Maria Luiza Brito de SousaAlves, L. C.Berne, M. E. 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