Estudo histoquímico das proteoglicanas da fáscia transversal e bainha anterior do músculo reto abdominal em homens adultos, portadores de hérnia inguinal tipo II e IIIA de NYHUS

BACKGROUND: To quantify the presence of proteoglycans in fascia transversalis and anterior sheath of the abdominal rectus muscle, from males, adults, with Nyhus type II and IIIA inguinal hernia. METHODS: The samples were divided in three groups: Group I - twenty patients with Nyhus type II inguinal...

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Detalhes bibliográficos
Autores: Silva, Evandro de Moraes e, Lopes Filho, Gaspar de Jesus [UNIFESP], Gonçalves, Rogério de Oliveira [UNIFESP]
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Brasil
Recursos:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/1703
Acesso em linha:http://dx.doi.org/10.1590/S0100-69912003000200009
http://repositorio.unifesp.br/handle/11600/1703
Access Level:acceso abierto
Palavra-chave:Hernia, inguinal
Heparan sulfate proteoglycan
Extracellular matrix
Fascia
Hérnia inguinal
Proteoglicano
Matriz extracelular
Fáscia
Descrição
Resumo:BACKGROUND: To quantify the presence of proteoglycans in fascia transversalis and anterior sheath of the abdominal rectus muscle, from males, adults, with Nyhus type II and IIIA inguinal hernia. METHODS: The samples were divided in three groups: Group I - twenty patients with Nyhus type II inguinal hernia; Group II - twenty patients with Nyhus type IIIa inguinal hernias. Group III - control comprised of ten cadavers with no more than 24 hours death and no hernias; Fascia transversalis and anterior sheath of the abdominal rectus muscle samples were collected and stained with alcian blue pH2,5. Computerized hystological evaluation (IMAGELAB) was used to analyse the samples prepared as described above. RESULTS: A smaller quantity of proteoglycan was found in patients with inguinal hernia as compared to control group and this was stastically significant. CONCLUSION: Patient with Nyhus type II and IIIa inguinal hernias had a smaller amount of proteoglycans in fascia transversalis and anterior sheath of the abdominal rectus muscle. The role of these findings regardind the etiology of inguinal hernias remains to be better evaluated by further research.