Recombinant vaccines and infectious bursal disease virus

Infectious Bursal Disease Virus (IBDV) is the etiological agent of Infectious Bursal Disease (IBD), an immunosuppressive and highly contagious disease that affects young birds causing important economic losses in the poultry industry worldwide. Currently, vaccination programmes with inactivated and...

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Detalhes bibliográficos
Autores: Lucero, María Soledad, Gómez, Evangelina Raquel, Carballeda, Juan Manuel, Gravisaco, María José, Chimeno Zoth, Silvina Andrea, Berinstein, Analía
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2012
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositório:CONICET Digital (CONICET)
Idioma:inglês
OAI Identifier:oai:ri.conicet.gov.ar:11336/199717
Acesso em linha:http://hdl.handle.net/11336/199717
Access Level:Acceso aberto
Palavra-chave:CHICKEN IMMUNE RESPONSE
INFECTIOUS BURSAL DISEASE
RECOMBINANT VACCINES
VP2
https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
Descrição
Resumo:Infectious Bursal Disease Virus (IBDV) is the etiological agent of Infectious Bursal Disease (IBD), an immunosuppressive and highly contagious disease that affects young birds causing important economic losses in the poultry industry worldwide. Currently, vaccination programmes with inactivated and live attenuated viruses have been used to prevent IBD. However, these vaccines present a number of disadvantages, mainly due to their viral nature. Consequently, in the last two decades, many studies have been conducted in order to replace conventional virus based vaccines by new, rationally designed vaccines that are safer as well as effective. In this review we will present a background on the disease and its causative agent, and focus on the development of new generation vaccines against this significant poultry disease.