Mechanism of the ultrastructural changes induced by partial hepatectomy in the STH cells of mice

The ultrastructural changes induced by partial hepatectomy in the STH cells of mice were examined. These changes suggest an increased secretory activity of STH cells. Therefore, several experimental procedures elucidating the possible mechanism of this effect were undertaken. Normal mice were starve...

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Detalles Bibliográficos
Autores: Gómez Dumm, César Leandro Alberto, Souto, M., Gagliardino, Juan José
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1980
País:Argentina
Institución:Universidad Nacional de La Plata
Repositorio:SEDICI (UNLP)
Idioma:inglés
OAI Identifier:oai:sedici.unlp.edu.ar:10915/143263
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/143263
Access Level:acceso abierto
Palabra clave:Ciencias Médicas
Biología
STH cells
cAMP
Glucagon
Partial hepatectomy
Descripción
Sumario:The ultrastructural changes induced by partial hepatectomy in the STH cells of mice were examined. These changes suggest an increased secretory activity of STH cells. Therefore, several experimental procedures elucidating the possible mechanism of this effect were undertaken. Normal mice were starved for 52 h or treated with insulin, glucagon, or cAMP. Serum glucose level measurements as well as electron microscopy of pituitary STH cells were carried out in each group of animals. It was found that STH cells of glucagon and cAMP-treated mice showed some of the ultrastructural features observed in partially hepatectomized animals.