Role of probiotics and functional foods in health: Gut immune stimulation by two probiotic strains and a potential probiotic yoghurt

There are numerous reports that show the benefits on the health attributed to the probiotic consumptions. Most of the studies were performed using animal models and only some of them were validated in controlled human trials. The present review is divided in two sections. In the first section we des...

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Detalles Bibliográficos
Autores: Maldonado Galdeano, María Carolina, Novotny Núñez, Ivanna, Carmuega, Esteban, de Moreno, Maria Alejandra, Perdigon, Gabriela del Valle
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/117975
Acceso en línea:http://hdl.handle.net/11336/117975
Access Level:acceso abierto
Palabra clave:MUCOSAL IMMUNITY
PROBIOTIC
PROBIOTIC CLAIMS
PROBIOTIC FERMENTED MILK
SYSTEMIC IMMUNITY
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
Descripción
Sumario:There are numerous reports that show the benefits on the health attributed to the probiotic consumptions. Most of the studies were performed using animal models and only some of them were validated in controlled human trials. The present review is divided in two sections. In the first section we describe how the probiotic microorganisms can interact with the intestinal epithelial cells that are the first line of cell in the mucosal site, focusing in the studies of two probiotic strains: Lactobacillus casei DN-114001 (actually Lactobacillus paracasei CNCMI-1518) and Lactobacillus casei CRL 431. Then we describe same beneficial effects attributed to probiotic administration and the administration of fermented milks containing these microorganisms or potential probiotic yoghurt, principally on the immune system and on the intestinal barrier in different experimental mouse models like enteropathogenic infection, malnutrition, cancer and intestinal inflammation.