The non-metathetic role of Grubbs’ carbene complexes: From hydrogen-free reduction of α,β-unsaturated alkenes to solid-supported sequential cross-metathesis/reduction
An efficient and high-yielding “hydrogen-free” reduction of α,β-unsaturated alkenes was carried out employing Grubbs' catalyst in a non-metathetic role and Et3SiH. Conditions were optimized under microwave irradiation. Application to the solid-phase organic synthesis allows a facile constructio...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2011 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/128082 |
| Acceso en línea: | http://hdl.handle.net/11336/128082 |
| Access Level: | acceso abierto |
| Palabra clave: | hydrogen free-reduction Grubbs catalyst sequential cross-metathesis/reduction Solid Phase https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Sumario: | An efficient and high-yielding “hydrogen-free” reduction of α,β-unsaturated alkenes was carried out employing Grubbs' catalyst in a non-metathetic role and Et3SiH. Conditions were optimized under microwave irradiation. Application to the solid-phase organic synthesis allows a facile construction of sp3–sp3 carbon bonds through a sequential cross metathesis/olefin reduction. |
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