Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)

The microstructure of polyampholyte gelatin hydrogels crosslinked covalently with fully hydrolyzed poly(vinyl alcohol) is characterized. The experimental methodology involves simple mechanical extension, spectroscopic and thermal methods (FTIR, XRD, DSC, TGA) and equilibrium swelling test to quantif...

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Detalhes bibliográficos
Autores: Porcaro, Andrea, Ottone, Mariel Lorena, Deiber, Julio Alcides
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/8870
Acesso em linha:http://hdl.handle.net/11336/8870
Access Level:acceso abierto
Palavra-chave:Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization
Hydrogel Mechanical Properties
Hydrogel Electrokinetic Properties
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
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spelling Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)Porcaro, AndreaOttone, Mariel LorenaDeiber, Julio AlcidesGelatin-Poly(Vinyl Alcohol) Hydrogel CharacterizationHydrogel Mechanical PropertiesHydrogel Electrokinetic Propertieshttps://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2The microstructure of polyampholyte gelatin hydrogels crosslinked covalently with fully hydrolyzed poly(vinyl alcohol) is characterized. The experimental methodology involves simple mechanical extension, spectroscopic and thermal methods (FTIR, XRD, DSC, TGA) and equilibrium swelling test to quantify relevant microstructural parameters and electrokinetic properties of this polyampholyte-polypeptide hydrogel, for a well defined range of crosslinker to gelatin mass ratios. These polyampholyte crosslinked matrices having different positive effective electrical charge are studied within an experimental and theoretical framework of their elastic and swelling properties. Estimations of average mesh size and toughness of the swollen hydrogels are provided. The feasibility of polyion complexation between positive crosslinked gelatin chains and negative bioactive macromolecules to be delivered through hydrogel biodegradation is analyzed. Several additional hydrogel properties are estimated like shear modulus, average molecular mass of network strands, swelling ratio, FloryeHuggins interaction parameter, hydrogel electrostatic zeta-potential and average effective charge number per chain before and after the crosslinking process to quantify gelatin chain cationization.Fil: Porcaro, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); ArgentinaFil: Ottone, Mariel Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); ArgentinaFil: Deiber, Julio Alcides. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); ArgentinaElsevier2013-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8870Porcaro, Andrea; Ottone, Mariel Lorena; Deiber, Julio Alcides; Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol); Elsevier; Polymer; 54; 11; 5-2013; 2706-27160032-3861enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.polymer.2013.03.045info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0032386113002644info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T14:01:28Zoai:ri.conicet.gov.ar:11336/8870instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 14:01:28.524CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
title Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
spellingShingle Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
Porcaro, Andrea
Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization
Hydrogel Mechanical Properties
Hydrogel Electrokinetic Properties
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
title_short Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
title_full Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
title_fullStr Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
title_full_unstemmed Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
title_sort Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
dc.creator.none.fl_str_mv Porcaro, Andrea
Ottone, Mariel Lorena
Deiber, Julio Alcides
author Porcaro, Andrea
author_facet Porcaro, Andrea
Ottone, Mariel Lorena
Deiber, Julio Alcides
author_role author
author2 Ottone, Mariel Lorena
Deiber, Julio Alcides
author2_role author
author
dc.subject.none.fl_str_mv Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization
Hydrogel Mechanical Properties
Hydrogel Electrokinetic Properties
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
topic Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization
Hydrogel Mechanical Properties
Hydrogel Electrokinetic Properties
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
description The microstructure of polyampholyte gelatin hydrogels crosslinked covalently with fully hydrolyzed poly(vinyl alcohol) is characterized. The experimental methodology involves simple mechanical extension, spectroscopic and thermal methods (FTIR, XRD, DSC, TGA) and equilibrium swelling test to quantify relevant microstructural parameters and electrokinetic properties of this polyampholyte-polypeptide hydrogel, for a well defined range of crosslinker to gelatin mass ratios. These polyampholyte crosslinked matrices having different positive effective electrical charge are studied within an experimental and theoretical framework of their elastic and swelling properties. Estimations of average mesh size and toughness of the swollen hydrogels are provided. The feasibility of polyion complexation between positive crosslinked gelatin chains and negative bioactive macromolecules to be delivered through hydrogel biodegradation is analyzed. Several additional hydrogel properties are estimated like shear modulus, average molecular mass of network strands, swelling ratio, FloryeHuggins interaction parameter, hydrogel electrostatic zeta-potential and average effective charge number per chain before and after the crosslinking process to quantify gelatin chain cationization.
publishDate 2013
dc.date.none.fl_str_mv 2013-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/8870
Porcaro, Andrea; Ottone, Mariel Lorena; Deiber, Julio Alcides; Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol); Elsevier; Polymer; 54; 11; 5-2013; 2706-2716
0032-3861
url http://hdl.handle.net/11336/8870
identifier_str_mv Porcaro, Andrea; Ottone, Mariel Lorena; Deiber, Julio Alcides; Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol); Elsevier; Polymer; 54; 11; 5-2013; 2706-2716
0032-3861
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.polymer.2013.03.045
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0032386113002644
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.223283

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