Disseminated Cutaneous Leishmaniasis in Colombia: Report of 27 Cases

ABSTRACT: Disseminated leishmaniasis (DL) is a poorly described disease that is frequently misdiagnosed as other clinical manifestations of cutaneous leishmaniasis (CL) such as diffuse CL or postkala-azar dermal leishmaniasis. Twenty-seven cases of DL diagnosed between 1997 and 2015 are described. A...

Descripción completa

Detalles Bibliográficos
Autores: Vélez Bernal, Iván Darío, Jiménez Echavarría, Alejandra María, Vásquez Hincapié, Daniel Alberto, Robledo Restrepo, Sara María
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Colombia
Institución:Universidad de Antioquia
Repositorio:Repositorio UdeA
Idioma:inglés
OAI Identifier:oai:bibliotecadigital.udea.edu.co:10495/32153
Acceso en línea:https://hdl.handle.net/10495/32153
Access Level:acceso abierto
Palabra clave:Leishmaniasis Cutánea
Leishmaniasis, Cutaneous
Leishmaniasis Cutánea Difusa
Leishmaniasis, Diffuse Cutaneous
Post-kala-azar dermal leishmaniasis
Descripción
Sumario:ABSTRACT: Disseminated leishmaniasis (DL) is a poorly described disease that is frequently misdiagnosed as other clinical manifestations of cutaneous leishmaniasis (CL) such as diffuse CL or postkala-azar dermal leishmaniasis. Twenty-seven cases of DL diagnosed between 1997 and 2015 are described. A higher prevalence was observed in men (mean age 32 years). The number of lesions per patient ranged from 12 to 294, distributed mainly in the upper extremities, face and trunk. The lesions were mostly plaques or nodules. Seven patients had nasal mucous damage, 74% of the patients were of mixed race, 92% lived in northwestern Colombia, and Leishmania (Viannia) panamensis was identified as the causative agent in 58% of cases. Eighteen patients recovered with pentavalent antimonial. The importance of distinguishing DL from those other clinical presentations is based on the fact that disseminated, diffuse and post-kala-azar CL are very different in etiology, clinical manifestations and response to treatment and prognosis.